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Ketosteroid monooxygenase : ウィキペディア英語版
Ketosteroid monooxygenase

Ketosteroid monooxygenase (, ''steroid-ketone monooxygenase'', ''progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)'', ''17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)'', ''androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)'') is an enzyme with system name ''ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)''. This enzyme catalyses the following chemical reaction
: ketosteroid + NADPH + H+ + O2 \rightleftharpoons steroid ester/lactone + NADP+ + H2O (general reaction)
:(1) progesterone + NADPH + H+ + O2 \rightleftharpoons testosterone acetate + NADP+ + H2O
:(2) androstenedione + NADPH + H+ + O2 \rightleftharpoons testololactone + NADP+ + H2O
:(3) 17alpha-hydroxyprogesterone + NADPH + H+ + O2 \rightleftharpoons androstenedione + acetate + NADP+ + H2O
Ketosteroid monooxygenase is a single FAD-containing enzyme that catalyses three types of monooxygenase reaction.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Ketosteroid monooxygenase」の詳細全文を読む



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